Your Complete Drug Reference —
Interactions, Comparisons & Costs
Trusted information on 256 medications across 21 drug classes. Look up uses, dosages, side effects, interactions, and cost-saving options in seconds.
Browse Medications by Condition
Find all approved medications for your diagnosis, with comparisons and cost information.
Anxiety Disorders
Anxiety disorders are the most common mental health conditions, characterized by excessive fear, worry, and related behavioral disturbances. They include generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobias.
View medications →Bacterial Infections
Bacterial infections are caused by pathogenic bacteria and can affect virtually any part of the body. Common bacterial infections include pneumonia, urinary tract infections, skin infections, and strep throat.
View medications →Chronic Kidney Disease (CKD)
Chronic kidney disease is a long-term condition where the kidneys do not work as well as they should. It is often caused by diabetes or high blood pressure and affects approximately 10% of the global population.
View medications →Heart Failure
Heart failure is a chronic condition where the heart cannot pump enough blood to meet the body's needs. It affects over 64 million people worldwide and is a leading cause of hospitalization in adults over 65.
View medications →Hyperlipidemia (High Cholesterol)
A condition characterized by abnormally elevated levels of lipids (cholesterol and/or triglycerides) in the blood.
View medications →Hyperlipidemia (High Cholesterol)
Hyperlipidemia is an abnormally high level of lipids (cholesterol and triglycerides) in the blood. It is a major risk factor for cardiovascular disease, heart attack, and stroke. It can be managed with lifestyle changes and medications.
View medications →Hypertension (High Blood Pressure)
A chronic condition where the force of blood against artery walls is consistently too high (≥130/80 mmHg).
View medications →Major Depressive Disorder
A common and serious mood disorder characterized by persistent sadness, loss of interest, and impaired daily functioning.
View medications →Obesity
A chronic disease defined by excess body fat accumulation (BMI ≥ 30) that impairs health.
View medications →Pain Management
Pain management encompasses the treatment of acute and chronic pain conditions. NSAIDs are among the most commonly used medications for pain relief, inflammation, and fever reduction.
View medications →Type 2 Diabetes
A chronic metabolic condition characterized by high blood sugar, insulin resistance, and relative insulin deficiency.
View medications →GLP-1 & Weight Loss Medications
Semaglutide, tirzepatide, liraglutide, and more — complete prescribing information, comparisons, and cost data.
Dulaglutide
Trulicity (dulaglutide) is a medication in a class called GLP-1 receptor agonists. It is used alongside diet and exercise to help adults and children aged 10 and older with type 2 diabetes manage their blood sugar levels. Additionally, for adults with type 2 diabetes who have heart disease or risk factors, Trulicity can help lower their risk of serious heart problems like heart attack or stroke.
Exenatide
Exenatide (brand name: Exenatide) is a medication in the GLP-1 receptor agonist class, used to help adults with type 2 diabetes manage their blood sugar levels. It works by mimicking a natural hormone in your body that helps release insulin when your blood sugar is high, thereby improving glycemic control when used with diet and exercise.
Liraglutide
Liraglutide (Victoza) is a type of medicine that mimics a natural hormone in your body. It is prescribed to help adults and children aged 10 and older with type 2 diabetes manage their blood sugar levels, and it can also lower the risk of serious heart problems like heart attack or stroke in adults with type 2 diabetes and existing heart disease. It works by helping your body release insulin when needed and reducing the amount of sugar your liver makes.
Semaglutide
Semaglutide is a once-weekly (or once-daily oral) GLP-1 receptor agonist that lowers blood sugar and reduces body weight by mimicking the natural gut hormone GLP-1. It is sold under three brand names — Ozempic (injectable, type 2 diabetes), Wegovy (injectable, weight management), and Rybelsus (oral tablet, type 2 diabetes) — all manufactured by Novo Nordisk. Clinical trials show it reduces HbA1c by up to 2.0 percentage points and body weight by up to 15% at the highest injectable dose.
Semaglutide
Semaglutide (Ozempic, Wegovy, Rybelsus) is a GLP-1 receptor agonist approved for type 2 diabetes, weight management, and cardiovascular risk reduction. See the full semaglutide monograph for complete prescribing information.
Tirzepatide
Tirzepatide is a once-weekly injectable prescription medication that activates both the GIP and GLP-1 hormone receptors — making it the first dual GIP/GLP-1 receptor agonist approved by the FDA. It is sold as Mounjaro for type 2 diabetes and as Zepbound for chronic weight management and obstructive sleep apnea. Clinical trials show it reduces HbA1c by up to 2.58 percentage points and body weight by up to 20.9% at the highest dose.
Protect your muscle mass on GLP-1 medications
Zova reduces GLP-1 muscle loss from 39% to 8.7% — validated by Lancet Diabetes research.
GLP-1 Guides & Resources
Wegovy vs. Zepbound: Which GLP-1 Weight Loss Drug Is More Effective?
Read more →
Mounjaro vs. Zepbound: Same Drug, Two FDA Approvals — Which Is Right for You?
Read more →
Mounjaro vs. Ozempic: Which GLP-1 Drug Is Right for You?
Read more →
Metformin Cost Without Insurance in 2026: What You'll Pay and How to Save
Read more →Top Drug Comparisons
Side-by-side analyses of the most commonly compared medication pairs.
Atorvastatin vs. Simvastatin: Comparing Two Common Cholesterol Medications
Atorvastatin (Lipitor) and simvastatin (Zocor) are both statin medications used to lower high cholesterol and reduce the risk of heart disease. Patients often compare these drugs due to their similar purpose, but they have differences in potency, dosing, and potential interactions.
Compare →Atorvastatin vs. Rosuvastatin: Comparing Two Common Statins
Atorvastatin (Lipitor) and rosuvastatin (Crestor) are both powerful statin medications used to lower high cholesterol and reduce the risk of heart disease. Patients often compare these drugs to understand their differences in effectiveness, side effects, and how they might fit into their treatment plan.
Compare →Lisinopril vs. Losartan: Comparing ACE Inhibitors and ARBs for Blood Pressure
Lisinopril and Losartan are both common prescription medications used to treat high blood pressure, heart failure, and protect the heart. While they achieve similar goals, they belong to different drug classes and have distinct mechanisms of action and side effect profiles. This guide will help you understand their key differences.
Compare →Browse by Drug Class
Explore all 21 drug classes — mechanism of action, member drugs, and cost comparisons.
Cheapest Generic Drugs
Common medications available as low-cost generics — often under $10/month with coupons.
Metformin Hydrochloride
Metformin Hydrochloride
$4-$25/month
Lisinopril
Prinivil
$4–$15/month
Atorvastatin
Lipitor
$4–$25/month
Simvastatin
Simvastatin
$4–$20/month
Amlodipine Besylate
Amlodipine Besylate
$4–$25/month
Omeprazole
Prilosec
$4–$25/month
Sertraline Hydrochloride
Sertraline hydrochloride
$10–$50/month
Losartan Potassium
Cozaar
$4–$15/month
Top 50 Most Prescribed Medications
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Drug Interaction Checker
Taking multiple medications? Check for potentially dangerous drug-drug interactions before combining prescriptions. Our database covers 256 drugs with clinically reviewed interaction data.
From the RxGuide Blog
In-depth guides on medications, side effects, and treatment decisions — reviewed by licensed pharmacists.
Wegovy vs. Zepbound: Which GLP-1 Weight Loss Drug Is More Effective?
Wegovy and Zepbound are both FDA-approved injectable medications for weight loss, but Zepbound produces 47% more weight loss in head-to-head trials.
Mounjaro vs. Zepbound: Same Drug, Two FDA Approvals — Which Is Right for You?
Mounjaro and Zepbound both contain tirzepatide, but are FDA-approved for different conditions. Learn the key differences in indications, cost, insurance coverage, and when to choose each drug.
Mounjaro vs. Ozempic: Which GLP-1 Drug Is Right for You?
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103
Drug comparisons
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